Corticosteroid joint injections
Corticosteroid injections (methylprednisolone or triamcinolone) are used to treat OA in the knee joints. Corticosteroids work by reducing inflammation and pain in the joint. The benefits of these injections usually last about 4 to 6 weeks. Because repeated injections can damage cartilage, you should have no more than 3 injections per joint per year. Other than this, side effects and interactions with other drugs are rare.
Hyaluronan joint injections
Hyaluronan is a substance found in the joint liquid known as synovial fluid. It cushions the joint and prevents the bones from rubbing together. Hyaluronan injections given in the knee help replace the synovial fluid that has lost its cushioning properties. A series of 3 to 5 injections can relieve knee pain due to OA for up to 6 months. Side effects and drug interactions are rare.